Regarding placebos in research, what is required?

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Multiple Choice

Regarding placebos in research, what is required?

Placebo use in research must be governed by informed consent. Respect for autonomy means participants have the right to know what may happen in a trial, including the possibility of being assigned to a placebo and not receiving active treatment, and to decide whether to participate. The consent process should explain that randomization could assign them to placebo, any potential lack of direct therapeutic benefit, the risks involved, available alternatives, and their right to withdraw at any time. This protects participants from deception and upholds ethical and legal standards for human research. The other statements aren’t correct because consent cannot be bypassed with approval alone, placebo use isn’t categorically banned in research, and consent from the participant—not just physician approval or ethics approval—is required to participate.

Placebo use in research must be governed by informed consent. Respect for autonomy means participants have the right to know what may happen in a trial, including the possibility of being assigned to a placebo and not receiving active treatment, and to decide whether to participate. The consent process should explain that randomization could assign them to placebo, any potential lack of direct therapeutic benefit, the risks involved, available alternatives, and their right to withdraw at any time. This protects participants from deception and upholds ethical and legal standards for human research.

The other statements aren’t correct because consent cannot be bypassed with approval alone, placebo use isn’t categorically banned in research, and consent from the participant—not just physician approval or ethics approval—is required to participate.

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